Target-based drug discovery has been highly successful. The main advantage of target-based approaches are that they are often simpler to execute than phenotypic approaches, operating with knowledge of a drug’s
molecular mechanisms from an earlier stage. The target based drug design (TBD) approaches are very important computational procedures, including visualization tools, to support the decision systems of new drug design and development. The
molecular dynamics simulation protocols are the bright spots in TBD approaches.
To achieve the full benefit of developing a successful drug, multidisciplinary approaches such as Rational drug design and literature knowledge would be necessary. Our team is well expertise in rational drug design. We identify the
target, based on predefined properties for targets, Once a target is identified, then the drugs be evaluated by binding scores (affinity/specificity), balance between hydrophilicity/lipophilicity, absorption, distribution, metabolism, and
excretion (ADME) respectively. This approach of drug design can be applied to develop drugs to treat a wide variety of diseases and can also be used for designing drugs for disease prevention.